Carolina Panthers vs New Orleans Saints opening odds | NFL Week 10 Opening Odds for Every Game (P…


Explore the latest developments concerning Carolina Panthers vs.

Carolina Panthers vs New Orleans Saints opening odds

The 5-4 Carolina Panthers are favored for the first time all season after upsetting the upstart Green Bay Packers. Now that the Panthers will be viewed hither and yon as the legitimate Super Bowl contenders they’ve always been, they can finally start to enjoy their season.

Last week, the Panthers were underdogs by a margin second only to the New Orleans Saints. The Panthers pulled up the biggest upset in Green Bay history while the Saints lived down to their billing. This week, the Panthers are favored by a mere 4.5 points against those same Saints with the game in Charlotte.

NFL Week 10 Opening Odds for Every Game (Packers Favored vs. Eagles, Rams Favored vs. 49ers)

The NFL is halfway through the 2025 season, and Week 10 features a loaded slate, including some crucial NFC matchups between the Los Angeles Rams and San Francisco 49ers and a Monday Night Football clash between the Philadelphia Eagles and Green Bay Packers.

There are four teams that won't suit up in Week 10, as the Kansas City Chiefs, Cincinnati Bengals, Tennessee Titans and Dallas Cowboys are all on the bye.

This week brings back international games, as the Atlanta Falcons and Indianapolis Colts will head across the pond to play in Berlin on Sunday morning. That's not the only standalone game to watch, as the Denver Broncos are massive favorites against the Las Vegas Raiders on Thursday night and the Los Angeles Chargers are favored on Sunday night against the Pittsburgh Steelers.

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Week 10 lookahead lines, picks: Best bets prior to Week 9 kickoff

We were able to get ahead of the big line move in Falcons-Patriots in last week's column, where we tipped Patriots -2.5 as a good play thinking that a potential win for them against the Browns would be more impressive than the Falcons beating the Dolphins considering how the Dolphins-Browns matchup went the previous week. Well, the Falcons no-showed in Miami with Kirk Cousins at QB, and now the line in this week's game is Patriots -5.5.

We were also able to get some good value on the Bears in Cincinnati, though some of that is tied to Joe Flacco's injury, which has that game at Bears -3 currently when they were laying just 1.5 points on the lookahead. And I mentioned that Broncos-Texans had the chance to tip through zero and move to the Texans being favored with Nico Collins potentially back this week, and while that has happened, a lot of that comes down to the Broncos losing Patrick Surtain II, an angle we couldn't have predicted last week.

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