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MLB DFS Picks: FanDuel Top Plays and Strategy for Saturday, May 16
Saturday's main slate at FanDuel has eight games and goes off at 7:10 p.m. EDT. In what may be a first in quite some time, White Sox starter Davis Martin ($10,300) is the slate's highest priced arm. Use him at your own peril. Jacob deGrom ($10,100) will surely be the more obvious/higher-rostered top arm.
The Mariners (-166) are the slate's biggest favorite, which isn't a massive number. The Rangers (-148) and Braves (-142) follow, and that's likely where I'll be targeting my pitching choices below. Giants – A's is our highest total at 9.5, while four more games come in at 8.5. Clearly not a high-scoring slate so perhaps there will be some bargain arms. Rain will not be a concern here, and wind likely won't play a massive factor either. Slightly blowing in in Minneapolis, and slightly blowing out in Anaheim and New York; very minimal impact.
Fantasy Baseball Cheat Sheet: Top DraftKings MLB DFS Plays for Saturday 5/16/26
DraftKings Network analysts give their top DraftKings daily fantasy baseball plays for today’s MLB slate.
Each day, DraftKings Network analysts give their favorite fantasy baseball picks for the main MLB DFS slate on DraftKings.
Below is a collection of top DraftKings fantasy baseball plays for today’s MLB slate.
Set your DraftKings fantasy baseball lineups here: MLB $100K Relay Throw [$25K to 1st]
To see all DraftKings DFS analysis, head over to the DraftKings Network Fantasy Advice page!
Read Stan’s full analysis here: MLB DFS Picks Today: Top DraftKings Targets and Values for Saturday 5/16/26
Read Zach’s full analysis here: MLB DFS Picks: Top Fantasy Baseball Value Plays for Saturday 5/16/26
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MLB DFS Picks Today (5/16): Covering The Bases with stlcardinals84
Long-time grinder Justin Van Zuiden (aka stlcardinals84) is here to cover the bases for the upcoming MLB DFS slate on DraftKings and FanDuel. Whether you are looking for the top pitchers or the best stacks, Justin has you covered with an extensive deep dive into his favorite MLB DFS picks today on May 16, 2026.
Happy Saturday, Grinders! We have the usual Saturday schedule with games spread out all over the place. There are 3 early starts followed by 3 later afternoon games and 8 evening games. DraftKings has combined all the afternoon games into one 6-game slate, whereas FanDuel has split them up into a pair of small slates. As such, I will focus on the DK early slate and the main evening slate in the article today.
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