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Scientists achieve pancreatic tumour regression in breakthrough study
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Spanish team cures pancreatic cancer in mice: The science behind it decoded
A team of scientists at the Spanish Cancer Research Centre has reported a major breakthrough that could change how pancreatic cancer is treated.
Led by renowned cancer biologist Mariano Barbacid, the researchers have managed to make pancreatic tumours completely and permanently disappear in experimental models using a powerful new drug combination.
Pancreatic ductal adenocarcinoma, the most common form of pancreatic cancer, is one of the deadliest cancers in the world. It is often diagnosed late, spreads quickly, and resists most existing treatments.
Fewer than one in ten patients survive five years after diagnosis, making new treatment strategies urgently needed.
Most pancreatic cancers are driven by a faulty gene called KRAS. This gene acts like a stuck accelerator pedal, constantly telling cancer cells to grow and divide. In recent years, scientists have developed drugs that block KRAS signals, raising hopes for better treatment.
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