When will George Kittle return? 49ers TE injury update | Is George Kittle Playing Tonight? (Injur…

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When will George Kittle return? 49ers TE injury update

There may be some hope on the horizon for the San Francisco 49ers. And his name is George Kittle.

The 49ers will have to make due without Kittle, as well as starting quarterback Brock Purdy and all three of their top receivers, when they face the Los Angeles Rams on Thursday night. But there's reason to believe Kittle, at least, will be back sooner rather than later.

San Francisco's star tight end has missed three straight games since he landed on injured reserve with a hamstring injury. Kittle suffered the injury in Week 1, and his stint on IR meant he would have to miss a minimum of four games.

Is George Kittle Playing Tonight? (Injury Update, Betting Impact for 49ers vs. Rams)

The San Francisco 49ers are down several weapons on offense on Thursday night, including star tight end George Kittle.

Kittle, who is currently on short-term injured reserve with a hamstring injury, is not eligible to return until Week 6. Kittle was injured in Week 1 against the Seattle Seahawks, and he must miss a minimum of four games before returning to action. So, Oct. 12 against the Tampa Bay Buccaneers will be the All-Pro's first chance to suit up again in 2025.

Prior to going down in Week 1, Kittle made four catches for 25 yards and a touchdown. Even though the 49ers have a ton of weapons out in Week 5 — including Brandon Aiyuk, Ricky Pearsall and Jauan Jennings — Kittle will not be able to play.

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Jan 29, 2023; Philadelphia, Pennsylvania, USA; A general view of San Francisco 49ers helmet on the bench before game against the Philadelphia Eagles in the NFC Championship game at Lincoln Financial Field. Mandatory Credit: Bill Streicher-USA TODAY Sports on October 1, 2025 The San Francisco 49ers are looking to avoid a fate similar to last season’s, when they missed out on the playoffs a season removed from making the playoffs. The Niners have managed to survive a host of injuries to key players early this season to get off to a 3-1 start on the year. The Niners got star…

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