Explore the latest developments concerning NFL Week 1.
NFL Week 1 betting: Odds, lines and totals for every game
The Philadelphia Eagles begin their Super Bowl title defense Thursday night against the Dallas Cowboys in the NFL's season opener. The Eagles are 7-point favorites against their NFC East rivals, and only one other game this week features a team favored by a touchdown or more (Denver Broncos -8 vs. Tennessee Titans).
A whopping 11 games have spreads of a field goal or less.
Not as surprising, the Sunday night matchup between the Baltimore Ravens and Buffalo Bills has the highest over/under in Week 1, at 52.5 points. Buffalo is a 1.5-point favorite at home in a rematch of last season's AFC divisional round, a game the Bills narrowly won.
Prisco's Week 1 NFL picks: Bills outlast Ravens, Jets beat Aaron Rodgers and Bears ruin J.J. McCarthy's debut
Let me start the 2025 NFL picks column with a factual statement:
It was not my best season when it came to NFL picks. I wasn't the worst of my CBSSports.com experts picks crew, but it wasn't very good. None of us really were.
It's a new season, which means like every fan base and every team, optimism is a part of my equation. I will be better. I have to be better.
Week 1 picks are always a challenge, but I feel pretty good about these. The record is 0-0 right now, so the slate is clean.
Last season is in the rear-view mirror, so let's get this damn season started — an quit showing my 2024 record.
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NFL will not play a Week 1 game on Friday next season due to federal law – The Athletic
Week 1 of NFL play will not include a Friday game next season, the league said Tuesday.
NFL executive vice president and COO Hans Schroeder confirmed during a conference call with reporters that the league cannot legally open its season the same way it has the past couple of years.
The change is due to an antitrust provision in the Sports Broadcasting Act of 1961 that bans broadcasts of professional football by any station within 75 miles of a high school or college football game. It specifies that pro games cannot run on any Friday or Saturday from the second Friday in September through the second Saturday in December.
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